3-Hydroxybakuchiol
Product Specifications
UNSPSC Description
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
Target Antigen
Apoptosis; Glycosidase
Type
Natural Products
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-hydroxybakuchiol.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(/C=C/[C@](C)(C=C)CC/C=C(C)\C)C=C1O
Molecular Weight
272.38
References & Citations
[1]Jaña F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64.|[2]Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1839/3-Hydroxybakuchiol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1839/
Clinical Information
No Development Reported
CAS Number
178765-54-3
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