Siomycin A
Product Specifications
CAS Number
12656-09-6
Target
Others, Apoptosis, Antibacterial
Related Pathways
Apoptosis, Microbiology/Virology, Others
Bioactivity
Siomycin A is a thiopeptide antibiotic that selectively inhibits Forkhead box M1 (FOXM1) without affecting other Forkhead box family members, exhibiting anti-tumor properties and promoting apoptosis.
Smiles
[H][C@]12CSC(=N1)C(NC(=O)C(NC(=O)c1csc(n1)[C@@]13CCC(=N[C@]1([H])c1csc(n1)[C@@]([H])(NC(=O)c1csc(n1)[C@@]([H])(NC2=O)[C@](C)(O)[C@@H](C)O)[C@@H](C)OC(=O)c1cc([C@H](C)O)c2C=C[C@@H](N[C@@H](C(C)C)C(=O)NC(=C)C(=O)NC(=C)C(=O)N[C@@H](C)C(=O)N3)[C@@]([H])(O)c2n1)c1nc(cs1)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)[C@@H](C)O)=CC |c:4,24,70|
Molecular Formula
C71H81N19O18S5
Molecular Weight
1648.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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