Siguazodan
Product Specifications
CAS Number
115344-47-3
Target
PDE
Related Pathways
Metabolism
Purity
0.9987
Bioactivity
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III) ) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.
Smiles
CN\C(NC#N)=N/c1ccc(cc1)C1=NNC(=O)CC1C
Molecular Formula
C14H16N6O
Molecular Weight
284.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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