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X5050

X5050 is a REST inhibitor, with an EC50 of 2.1 μM[1].

Product Specifications

CAS Number

2404756-81-4

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/x5050.html

Purity

98.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C2N=C(C3=CC=CC=C3O)NC2=C1)NOCC=C

Molecular Formula

C17H15N3O3

Molecular Weight

309.32

References & Citations

[1]Jérémie Charbord, et al. High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes. Stem Cells. 2013 Sep;31 (9) :1816-28.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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