SI-109

2429877-30-3

Ligands for Target Protein for PROTAC, STAT

JAK/STAT signaling, Stem Cells, PROTAC

SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM), and with antitumor activity.

O=C([C@@H](NC([C@@H]1CC[C@H](CCN(C(C)=O)C[C@@H]2NC(C3=CC(C=C(C(F)(P(O)(O)=O)F)C=C4)=C4N3)=O)N1C2=O)=O)CCC(N)=O)NC(C5=CC=CC=C5)C6=CC=CC=C6

C40H44F2N7O9P

835.79

Ice Packs

-20°C