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Talmapimod hydrochloride

Product Specifications

CAS Number

309915-12-6

Target

P38 MAPK

Related Pathways

MAPK

Bioactivity

Talmapimod hydrochloride is a selective and ATP-competitive p38? inhibitor (IC50: 9 nM) . It also shows about 10-fold selectivity over p38?, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Smiles

Cl.C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

Molecular Formula

C27H31Cl2FN4O3

Molecular Weight

549.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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