Talmapimod
Product Specifications
CAS Number
309913-83-5
Target
P38 MAPK
Related Pathways
MAPK
Purity
>99.99%
Bioactivity
Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
Smiles
C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C
Molecular Formula
C27H30ClFN4O3
Molecular Weight
513
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
CS0005-724421 1 Each
12 Cell Culture Inserts+12 Well Plate, 1.0 μm, PET Membrane, Opaque, TC, Sterile, 12/pk, 48/cs
Sign In for Pricing
View Details VAng-Lsx04914-1mgEcoli 1 mg (E. coli)
Recombinant Mycoplasma Pneumoniae MPN_343 Protein (aa 1-330)
Sign In for Pricing
View Details MBS6340131-01 0.2 mL
RALBP1, NT (RALBP1, RLIP1, RLIP76, RalA-binding protein 1, 76kD Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, Ral-interacting protein 1) (APC)
Sign In for Pricing
View Details MBS6340131-02 5x 0.2 mL
RALBP1, NT (RALBP1, RLIP1, RLIP76, RalA-binding protein 1, 76kD Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, Ral-interacting protein 1) (APC)
Sign In for Pricing
View Details