Talmapimod
Product Specifications
CAS Number
309913-83-5
Target
P38 MAPK
Related Pathways
MAPK
Purity
>99.99%
Bioactivity
Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
Smiles
C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C
Molecular Formula
C27H30ClFN4O3
Molecular Weight
513
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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