Obestatin (rat)

Obestatin (rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. Obestatin (rat) suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin is an endogenous ligand of G-protein coupled receptor 39 (GPR39) . Obestatin (rat) has anti-inflammatory, anti-myocardial infarction and antioxidant activities[1][2].

Product Specifications

CAS Number

[869705-22-6]

UNSPSC

12352209

Target

GPR39

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/obestatin-rat.html

Purity

98.73

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC4=CNC=N4)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=CC=C5)N

Molecular Formula

C114H174N34O31

Molecular Weight

2516.81

References & Citations

[1]Azadeh Toosi, et al. Obestatin Improve Spatial Memory Impairment in a Rat Model of Fetal Alcohol Spectrum Disorders via Inhibiting Apoptosis and Neuroinflammation. Neuropeptides. 2019 Apr;74:88-94.|[2]Science. 2005 Nov 11;310 (5750) :996-9. doi: 10.1126/science.1117255.