Ethiazide

Ethiazide is a thiazole diuretic which inhibits renal reabsorption of sodium and water, thereby increasing urine excretion, reducing fluid retention, and lowering blood volume and blood pressure. Ethiazide can be used for cardiovascular research[1].

Product Specifications

CAS Number

[1824-58-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Natriuretic Peptide Receptor (NPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ethiazide.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=C(C=C(NC(NS2(=O)=O)CC)C2=C1)Cl)(N)=O

Molecular Formula

C9H12ClN3O4S2

Molecular Weight

325.79

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Aso Y, et al. Epimerization and racemization of some chiral drugs in the presence of human serum albumin. Chem Pharm Bull (Tokyo) . 1990 Jan;38 (1) :180-4.