S119-8
Product Specifications
CAS Number
443639-96-1
Target
Influenza Virus
Related Pathways
Microbiology/Virology
Purity
0.9983
Bioactivity
RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.
Smiles
CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc(Nc2ccccc2)cc1
Molecular Formula
C23H24N2O
Molecular Weight
344.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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