RV01
Product Specifications
CAS Number
1016897-10-1
Target
TLR|||MAPK|||NF-?B|||Dehydrogenase
Related Pathways
Metabolism|||MAPK|||NF-?B|||Immunology/Inflammation
Purity
0.9993
Bioactivity
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduces iNOS expression and has anti-neuroinflammatory effects. rV01 reduces tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion. RV01 reduced tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion, inhibited lps-induced ROS production and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation, decreased toll-like receptor 4 (TLR4) protein expression, and inhibited lps-induced activation of mitogen-activated protein kinase (MAPK) and nuclear transcription factor-?B (NF-?B) signaling pathways.
Smiles
Oc1cc(O)cc(\C=C\c2ccnc3ccccc23)c1
Molecular Formula
C17H13NO2
Molecular Weight
263.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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