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RTI-13951-33 hydrochloride

Product Specifications

Target

Others, GPCR

Related Pathways

Others, GPCR/G Protein, Endocrinology/Hormones

Bioactivity

RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist, exhibiting an EC50 of 25 nM in vitro cAMP functional assay. It significantly reduces alcohol reinforcement and intake behaviors in rats [1].

Smiles

COCC1=CC=C(C2=CC=C(N(C[C@@H](N)[C@@H](C)OC)C([C@H]3[C@H](C4=CC=CC=N4)C3)=O)C=C2)C=C1.Cl.Cl

Molecular Formula

C28H35Cl2N3O3

Molecular Weight

532.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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