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RR-11a analog

Product Specifications

CAS Number

685543-66-2

Target

Gamma-secretase, Parasite

Related Pathways

Proteases/Proteasome, Stem Cells, Neuroscience, Microbiology/Virology

Purity

0.988

Bioactivity

RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.

Smiles

CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1

Molecular Formula

C22H29N5O8

Molecular Weight

491.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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