RR-11a analog
Product Specifications
CAS Number
685543-66-2
Target
Gamma-secretase, Parasite
Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience, Microbiology/Virology
Purity
0.988
Bioactivity
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.
Smiles
CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1
Molecular Formula
C22H29N5O8
Molecular Weight
491.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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