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RORγt Inverse agonist 3

Product Specifications

CAS Number

2364429-77-4

Target

Others, ROR

Related Pathways

Others, Metabolism

Bioactivity

RORγt Inverse Agonist 3 is a potent, selective, and orally active inverse agonist of RORγ with EC50 values of 0.22 μM for hRORγ and 0.15 μM for RORγt (human IL-17 cells), respectively.

Smiles

CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(nc23)C(C)C)-c2cncn2C)c1Cl

Molecular Formula

C29H31Cl2N5O4S

Molecular Weight

616.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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