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Riviciclib

Product Specifications

CAS Number

920113-02-6

Target

Others, CDK

Related Pathways

Cell Cycle/Checkpoint, Others

Bioactivity

Riviciclib is a potent inhibitor of cyclin-dependent kinase (CDK) (CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively), with antitumor activity on cisplatin-resistant cells.

Smiles

OC=1C(=C2C(C(=O)C=C(O2)C3=C(Cl)C=CC=C3)=C(O)C1)[C@H]4[C@H](CO)N(C)CC4

Molecular Formula

C21H20ClNO5

Molecular Weight

401.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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