RAF mutant-IN-1

2340020-82-6

Others|||Raf

MAPK|||Others

RAF mutant-IN-1 is an inhibitor of RAF kinase (IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively) .

O=C(C1=CSC2=C1N=CN=C2N)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(C(Cl)=C5F)O.Cl.Cl

C23H18Cl3FN6O2S

567.85

Cool pack

-20°C