PF-06250112
Product Specifications
CAS Number
1609465-89-5
Target
BTK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively) .
Smiles
C(N)(=O)C=1C(=NN(C1N)[C@@H]2CN(C#N)CCC2)C3=CC=C(OC4=C(F)C=C(F)C=C4)C=C3
Molecular Formula
C22H20F2N6O2
Molecular Weight
438.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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