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SSH3 (phospho-Ser37) rabbit pAb

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. 2002 [PubMed 11832213]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]

UniProt

Q8TE77

Swiss Prot

Q8TE77

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human SSH3 (Ser37)

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Molecular Weight

74kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

74kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Nucleus .

Other Product Names

Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)

Gene ID (Human)

54961

Available Sizes

Curated Selection

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