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R916562

Product Specifications

CAS Number

1037798-41-6

Target

VEGFR, TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

R916562 is an orally active, selective Axl/VEGF-R2 inhibitor with IC50 values of 136 nM and 24 nM, respectively, demonstrating anti-angiogenesis and anti-metastasis properties.

Smiles

CC=1C=2C(=C(N=C(Cl)N2)N3N=C(NC4=CC=C(C=C4)N5CCN(CC5)[C@H]6[C@]7(C[C@@](C6)(CC7)[H])[H])N=C3N)SC1

Molecular Formula

C26H30ClN9S

Molecular Weight

536.09

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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