R916562
Product Specifications
CAS Number
1037798-41-6
Target
VEGFR, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
R916562 is an orally active, selective Axl/VEGF-R2 inhibitor with IC50 values of 136 nM and 24 nM, respectively, demonstrating anti-angiogenesis and anti-metastasis properties.
Smiles
CC=1C=2C(=C(N=C(Cl)N2)N3N=C(NC4=CC=C(C=C4)N5CCN(CC5)[C@H]6[C@]7(C[C@@](C6)(CC7)[H])[H])N=C3N)SC1
Molecular Formula
C26H30ClN9S
Molecular Weight
536.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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