NIC
NIC is a host invasion inhibitor. NIC can suppress host invasion by interacting with the major invasion-related protein, merozoite surface protein 1 (MSP-1) . NIC prevents the invasion of Plasmodium falciparum and Plasmodium vivax into the host[1].
Product Specifications
CAS Number
114773-20-5
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nic.html
Smiles
O=CC1=C(N=C(CCCC)N1CC2=CC=C([N+]([O-])=O)C=C2)Cl
Molecular Formula
C15H16ClN3O3
Molecular Weight
321.76
References & Citations
[1]Chandramohanadas R, et al. Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species. J Infect Dis. 2014 Nov 15;210 (10) :1616-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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