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(R)-FL118

Product Specifications

UNSPSC Description

(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1].

Target Antigen

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-fl118.html

Solubility

DMSO : 2.7 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC6=C(OCO6)C=C5C=C4C3)=C2)=O)O

Molecular Weight

392.36

References & Citations

[1]Del Poeta M, et al. Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. Antimicrob Agents Chemother. 1999 Dec;43(12):2862-8.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15792/R-FL118-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15792/R-FL118-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

151636-76-9

Available Sizes

Curated Selection

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