(R) -FL118
(R) -FL118 (10,11- (Methylenedioxy) -20 (R) -camptothecin) is the R-enantiomer of FL118 (HY-12486) . (R) -FL118 shows anticancer activity[1].
Product Specifications
CAS Number
[151636-76-9]
Product Name Alternative
10,11- (Methylenedioxy) -20 (R) -camptothecin
UNSPSC
12352005
Hazard Statement
H301
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-fl118.html
Purity
99.94
Solubility
DMSO : 2.7 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC6=C(OCO6)C=C5C=C4C3)=C2)=O)O
Molecular Formula
C21H16N2O6
Molecular Weight
392.36
Precautions
H301
References & Citations
[1]Del Poeta M, et al. Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. Antimicrob Agents Chemother. 1999 Dec;43 (12) :2862-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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