(R)-FL118
Product Specifications
UNSPSC Description
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1].
Target Antigen
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-fl118.html
Solubility
DMSO : 2.7 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC6=C(OCO6)C=C5C=C4C3)=C2)=O)O
Molecular Weight
392.36
References & Citations
[1]Del Poeta M, et al. Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. Antimicrob Agents Chemother. 1999 Dec;43(12):2862-8.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15792/R-FL118-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15792/R-FL118-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
151636-76-9
Available Sizes
Curated Selection
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