Pyrotinib dimaleate
Product Specifications
CAS Number
1397922-61-0
Target
HER, EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9952
Bioactivity
Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor with IC50 values of 13 and 38 nM, respectively, for the treatment of HER2-positive breast cancer.
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OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C
Molecular Formula
C40H39ClN6O11
Molecular Weight
815.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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