PXS-5153A monohydrochloride
Product Specifications
Target
Monoamine Oxidase, Others
Related Pathways
Neuroscience, Others
Bioactivity
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced LOXL2-mediated collagen oxidation and collagen crosslinking in vitro which may represent an innovative therapeutic approach for the treatment of fibrosis
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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