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PROTAC EED degrader-1

Product Specifications

Target

PROTACs, Histone Methyltransferase

Related Pathways

PROTAC, Chromatin/Epigenetic

Bioactivity

PROTAC EED degrader-1, a PROTAC targeting EED (pKD = 9.02), is an inhibitor of polycomb repressive complex 2 (PRC2) with a pIC50 of 8.17.

Smiles

FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(NCCOC5=CC=C(OCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O)C=C5)=O)C=C4)C9=NN=CN39

Molecular Formula

C55H60FN11O8S

Molecular Weight

1054.2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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