PROTAC EED degrader-1
Product Specifications
Target
PROTACs, Histone Methyltransferase
Related Pathways
PROTAC, Chromatin/Epigenetic
Bioactivity
PROTAC EED degrader-1, a PROTAC targeting EED (pKD = 9.02), is an inhibitor of polycomb repressive complex 2 (PRC2) with a pIC50 of 8.17.
Smiles
FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(NCCOC5=CC=C(OCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O)C=C5)=O)C=C4)C9=NN=CN39
Molecular Formula
C55H60FN11O8S
Molecular Weight
1054.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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