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Rilzabrutinib

Product Specifications

CAS Number

1575596-29-0

Target

EGFR, HER, BTK

Related Pathways

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Purity

0.9976

Bioactivity

Rilzabrutinib (PRN1008) is a reversible covalent, selective, and orally active inhibitor of Bruton's Tyrosine Kinase (BTK) with an IC50 of 1.3 nM.

Smiles

CC(C)(\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCN(CC1)C1COC1

Molecular Formula

C36H40FN9O3

Molecular Weight

665.76

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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