PQCA
Product Specifications
CAS Number
1144504-35-7
Target
AChR
Related Pathways
Neuroscience
Purity
0.9988
Bioactivity
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity against other muscarinic receptors. PQCA is a potential compound for reducing cognitive deficits associated with Alzheimer's disease.
Smiles
OC(=O)c1cc(CN2CCC(CC2)(C#N)c2ccccn2)c2ccccn2c1=O
Molecular Formula
C22H20N4O3
Molecular Weight
388.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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