Cyclo (L-Pro-L-Val)
Product Specifications
CAS Number
2854-40-2
Target
COX|||I?B/IKK|||NOS|||NF-?B|||Antibacterial
Related Pathways
Microbiology/Virology|||Immunology/Inflammation|||NF-?B|||Neuroscience
Purity
0.9818
Bioactivity
Cyclo (L-Pro-L-Val), a 2,5-diketopiperazine extracted from the fruits of Mycobacterium chiliolyticum AZ2 and Mycobacterium leprae, possesses anti-inflammatory activity and virulence activity against phytopathogenic microorganisms (e.g., R. fascians LMG 3605) and inhibits Gram-positive plant pathogens.Cyclo (L-Pro-L-Val) significantly inhibited IKK? phosphorylation and I?B? and NF-?B activation as well as iNOS and COX-2 activation in a concentration Cyclo (L-Pro-L-Val) significantly inhibited the phosphorylation of IKK?, IKK?, I?B?, and NF-?B, as well as the activation of iNOS and COX-2 in a concentration-dependent manner, and is a potential therapeutic agent for the treatment of inflammation-related diseases.
Smiles
CC(C)[C@@H]1NC(=O)[C@@H]2CCCN2C1=O
Molecular Formula
C10H16N2O2
Molecular Weight
196.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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