Uzansertib phosphate
Product Specifications
CAS Number
2088852-47-3
Target
Pim
Related Pathways
JAK/STAT signaling, Chromatin/Epigenetic
Purity
0.9985
Bioactivity
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase (PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively) .
Smiles
O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.O=P(O)(O)O
Molecular Formula
C26H29F3N5O7P
Molecular Weight
611.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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