Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PIM447

Product Specifications

CAS Number

1210608-43-7

Target

Pim, Apoptosis

Related Pathways

Apoptosis, Chromatin/Epigenetic, JAK/STAT signaling

Purity

0.9897

Bioactivity

PIM447 (LGH447) is an oral, selective pan-PIM kinase inhibitor with antitumor and bone-protective effects. It inhibits PIM1, PIM2, and PIM3, induces apoptosis, and decreases the viability, proliferation, and motility of HuH6 and COA67 cells. PIM447 suppresses tumorigenesis in hepatocellular carcinoma and can be used in the study of multiple myeloma.

Smiles

FC1=C(N=C(C(NC=2C(=CC=NC2)[C@@H]3C[C@H](C)C[C@H](N)C3)=O)C=C1)C4=C(F)C=CC=C4F

Molecular Formula

C24H23F3N4O

Molecular Weight

440.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MDC1 CRISPR Activation Plasmid (m2)
sc-433741-ACT-2 20 µg

MDC1 CRISPR Activation Plasmid (m2)

Sign In for Pricing
View Details
Lentiviral mouse Nlrp4b shRNA (UAS) - Lentiviral mouse Nlrp4b shRNA (UAS, GFP) (100)
GTR15106665 1 Vial

Lentiviral mouse Nlrp4b shRNA (UAS) - Lentiviral mouse Nlrp4b shRNA (UAS, GFP) (100)

Sign In for Pricing
View Details
ABCD1 Rabbit Monoclonal Antibody
AMRe86668-01 1 Each

ABCD1 Rabbit Monoclonal Antibody

Sign In for Pricing
View Details
ABCD1 Rabbit Monoclonal Antibody
AMRe86668-02 50 µL

ABCD1 Rabbit Monoclonal Antibody

Sign In for Pricing
View Details
ABCD1 Rabbit Monoclonal Antibody
AMRe86668-03 100 µL

ABCD1 Rabbit Monoclonal Antibody

Sign In for Pricing
View Details
ATF1 antibody
MBS534467 Inquire

ATF1 antibody

Sign In for Pricing
View Details