Acrivastine
Acrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis.
Product Specifications
CAS Number
87848-99-5
Product Name Alternative
BW825C
UNSPSC
12352005
Hazard Statement
H413
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Acrivastine.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(O)/C=C/C1=NC(/C(C2=CC=C(C)C=C2)=C/CN3CCCC3)=CC=C1
Molecular Formula
C22H24N2O2
Molecular Weight
348.44
Precautions
H413
References & Citations
[1]Brogden RN, et al. Acrivastine. A review of its pharmacological properties and therapeutic efficacy in allergic rhinitis, urticaria and related disorders. Drugs. 1991 Jun;41 (6) :927-40.|[2]Gibbs TG, et al. Acrivastine in two doses compared with placebo in a multicentre, parallel group study for the treatment of seasonal allergic rhinitis. Br J Clin Pract. 1989 Jan;43 (1) :11-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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