PF-04634817 succinate
Product Specifications
CAS Number
2140301-98-8
Target
CCR, COX
Related Pathways
Microbiology/Virology, Neuroscience, Immunology/Inflammation, GPCR/G Protein
Bioactivity
PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5, exhibiting comparable human and rodent CCR2 potency with an IC50 of 20.8 nM.
Smiles
C(CC(O)=O)C(O)=O.C(=O)([C@]1(C(C)C)C[C@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3[C@@H]4CN([C@H](C3)C4)C=5C=C(C(F)(F)F)N=CN5
Molecular Formula
C29H42F3N5O7
Molecular Weight
629.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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