Penitrem A
Product Specifications
CAS Number
12627-35-9
Target
Others
Related Pathways
Others
Bioactivity
Penitrem A is an indole-diterpenoid neurotoxic alkaloid produced by *Penicillium* species. As a selective BK channel antagonist, it exhibits antiproliferative and anti-invasive activities against various malignancies, and stimulates the spontaneous release of endogenous glutamate, GABA, and aspartate from cortical synaptosomes. It is commonly used to induce tremor models in animals.
Smiles
[H][C@@]12O[C@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)c5[nH]c6cc(Cl)c7CC(=C)[C@@]8([H])C[C@@]9([H])[C@@]8(O)c7c6c5[C@@]([H])(OC9(C)C)[C@]4([H])CC[C@@]13O)O[C@@H]([C@@H]2O)C(C)=C
Molecular Formula
C37H44ClNO6
Molecular Weight
634.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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