Pemigatinib
Product Specifications
CAS Number
1513857-77-6
Target
FGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9995
Bioactivity
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR, with IC50 values of 0.4 nM for FGFR1, 0.5 nM for FGFR2, 1.2 nM for FGFR3, and 30 nM for FGFR4.
Smiles
O=C(N1CC)N(C2=C(F)C=C(OC)C(OC)=C2F)CC3=C1C4=C(N=C3)NC(CN5CCOCC5)=C4
Molecular Formula
C24H27F2N5O4
Molecular Weight
487.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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