PD 90780
Product Specifications
CAS Number
77422-99-2
Target
Others, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors, Others
Purity
0.9922
Bioactivity
PD 90780 is a non-peptide antagonist of nerve growth factor (NGF) that interacts with NGF and prevents it from binding to p75NTR, inhibiting the NGF-p75NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively.
Smiles
Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O
Molecular Formula
C19H14N4O4
Molecular Weight
362.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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