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PD 123319 ditrifluoroacetate

Product Specifications

CAS Number

136676-91-0

Target

RAAS

Related Pathways

Endocrinology/Hormones

Bioactivity

PD 123319 ditrifluoroacetate is a selective, non-peptide angiotensin II type 2 (AT2) receptor antagonist, and PD 123319 ditrifluoroacetate demonstrates potent activity with IC50 values of 34 nM in rat adrenal tissue and 210 nM in rat brain, thereby providing a valuable pharmacological tool for elucidating AT2 receptor function in cardiovascular and renal physiology and supporting research in hypertension and related disorders.

Smiles

OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C

Molecular Formula

C35H34F6N4O7

Molecular Weight

736.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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