PD 123319 ditrifluoroacetate
Product Specifications
CAS Number
136676-91-0
Target
RAAS
Related Pathways
Endocrinology/Hormones
Bioactivity
PD 123319 ditrifluoroacetate is a selective, non-peptide angiotensin II type 2 (AT2) receptor antagonist, and PD 123319 ditrifluoroacetate demonstrates potent activity with IC50 values of 34 nM in rat adrenal tissue and 210 nM in rat brain, thereby providing a valuable pharmacological tool for elucidating AT2 receptor function in cardiovascular and renal physiology and supporting research in hypertension and related disorders.
Smiles
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
Molecular Formula
C35H34F6N4O7
Molecular Weight
736.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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