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PAT-505

Product Specifications

CAS Number

1782070-22-7

Target

PDE, EGFR

Related Pathways

JAK/STAT signaling, Angiogenesis, Metabolism, Tyrosine Kinase/Adaptors

Purity

0.9884

Bioactivity

PAT-505 is an orally available, selective and potent inhibitor of autologous epidermal growth factor (IC50 2 nM in Hep3B cells, 9.7 nM in human blood, 62 nM in mouse plasma) .

Smiles

CCn1cc(cn1)-n1c(C2CC2)c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c12

Molecular Formula

C23H18ClF2N3O2S

Molecular Weight

473.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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