ORM-10103
Product Specifications
CAS Number
488847-28-5
Target
Na+/Ca2+ Exchanger, Calcium Channel
Related Pathways
Metabolism, Membrane transporter/Ion channel
Purity
0.999
Bioactivity
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX) .ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nM at -80 and 20 mV, respectively, and reduced early and delayed postdepolarization in canine hearts.
Smiles
[O-][N+](=O)c1ccc(Oc2ccc3OC(CCc3c2)c2ccccc2)nc1
Molecular Formula
C20H16N2O4
Molecular Weight
348.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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