Tirabrutinib hydrochloride
Product Specifications
CAS Number
1439901-97-9
Target
Apoptosis, BTK
Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.9995
Bioactivity
Tirabrutinib hydrochloride is a potent, highly selective, and irreversible oral BTK inhibitor. Tirabrutinib hydrochloride irreversibly covalently binds to Bruton tyrosine kinase (BTK) in B cells and exhibits potent in vitro cytotoxicity against many types of B cell malignancies, as well as in vivo antitumor activity in mouse models [1].
Smiles
Cl.CC#CC(=O)N1CC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O
Molecular Formula
C25H23ClN6O3
Molecular Weight
490.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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