ON 146040
Product Specifications
CAS Number
1404231-34-0
Target
PI3K, Bcr-Abl
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Purity
0.9989
Bioactivity
ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.
Smiles
CN1CCN(CC1)c1ccc(Nc2ncc3NC(=O)\C(Sc3n2)=C\c2ccc(cc2)[N+]([O-])=O)cc1
Molecular Formula
C24H23N7O3S
Molecular Weight
489.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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