NV03
Product Specifications
CAS Number
2448341-58-8
Target
Histone Methyltransferase, E1/E2/E3 Enzyme, Ligand for E3 Ligase
Related Pathways
PROTAC, Chromatin/Epigenetic, Ubiquitination
Purity
0.9988
Bioactivity
NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM), binding to the UHRF1 tandem Tudor domain (TTD) to form a complex. It is suitable for cancer research. NV03 also functions as a ligand for E3 ligases in PROTAC synthesis.
Smiles
CCN(CC)CCCNC(=O)Cn1nc(C)n2c3ccsc3c(C)c2c1=O
Molecular Formula
C19H27N5O2S
Molecular Weight
389.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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