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NCT-505

Product Specifications

CAS Number

2231079-74-4

Target

Dehydrogenase

Related Pathways

Metabolism

Purity

0.9993

Bioactivity

NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 ?M, 22.8 ?M, 20.1 ?M, and >57 ?M, respectively.

Smiles

CS(=O)(=O)N1CCN(CC1)C(=O)c1cnc2ccc(F)cc2c1N1CCC(CC1)(C#N)c1ccccc1

Molecular Formula

C27H28FN5O3S

Molecular Weight

521.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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