Nav1.1 activator 1
Product Specifications
CAS Number
2332897-85-3
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Nav1.1 activator 1 (compound 4) is an effective Nav1.1 agonist with blood-brain barrier permeability, exhibiting significant selectivity for Nav1.2, Nav1.5, and Nav1.6. It increases the decay time constant of Nav1.1 at 0.03 μM current and can be used for studying central nervous system disorders.
Smiles
C(NC=1C=CC(C(C)C)=NC1)(=O)C=2C(=CC=NC2N3C[C@@H](F)CC3)C4=C(F)C=CC(F)=C4
Molecular Formula
C24H23F3N4O
Molecular Weight
440.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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