Naquotinib mesylate
Product Specifications
CAS Number
1448237-05-5
Target
EGFR
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Bioactivity
Naquotinib mesylate (ASP8273 (mesylate) ) is an orally available, mutant-selective and irreversible inhibitor of EGFR (iC50s of 8-33 nM and 230 nM for toward EGFR mutants and EGFR) .
Smiles
CS(O)(=O)=O.CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C
Molecular Formula
C31H46N8O6S
Molecular Weight
658.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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